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  • Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1.

Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1.

Biomolecular NMR assignments (2010-05-04)
Sebastian Hiller, Thomas J Malia, Robert G Garces, Vladislav Y Orekhov, Gerhard Wagner
ABSTRACT

The voltage dependent anion channel (VDAC) forms a channel for metabolites and nutrients in the outer membrane of mitochondria, and it is also involved in apoptotic pathways. Here, we report sequence-specific NMR assignments for the isoform 1 of human VDAC reconstituted in lauryldimethylamine oxide (LDAO) detergent micelles. The assignments were deposited in the BMRB data base with accession number 16381.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
N,N-Dimethyldodecylamine N-oxide solution, ~30% in H2O
Sigma-Aldrich
N,N-Dimethyldodecylamine N-oxide, BioXtra, ≥99.0% (NT)