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  • Scintigraphic imaging with a peptide glucuronide in rabbits: 99mTc- exorphin C glucuronide.

Scintigraphic imaging with a peptide glucuronide in rabbits: 99mTc- exorphin C glucuronide.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine (2006-11-18)
T Ertay, P Unak, F Z Biber, C Tasci, F Zihnioğlu, H Durak
ABSTRACT

A peptide glucuronide (Exorphin C glucuronide) was labeled with 99mTc using glucoheptonate (GH) as a bifunctional chelating agent. Scintigraphic imaging was performed in male Albino rabbits. Exorphin C glucuronide showed rapid and efficient labeling with 99mTc using glucoheptonate as a bifunctional chelate. Results demonstrated that 99mTc-GEG may be a useful new type of glucuronide derivative of peptides for diagnosis of some cancer diseases.