- Revisit to (Z)-civetone synthesis.
Revisit to (Z)-civetone synthesis.
Natural product communications (2012-08-23)
Hisahiro Hagiwara, Teppei Adachi, Tomomi Nakamura, Takashi Hoshi, Toshio Suzuki
PMID22908580
ABSTRACT
The synthesis of (Z)-civetone (1) is described starting from oleic acid (5) via a series of reactions, intermolecular olefin self-metathesis, bromination/dehydrobromination into acetylene, semi-hydrogenation and intramolecular Dieckmann macrocyclization.