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[The vertebral artery syndrome and patient management tactics].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2013-02-08)
E A Panteleeva
ABSTRACT

The data of literature on vertebral artery syndrome, its clinical presentations, etiology and pathogenesis are summarized. Based on the own studies, the author considers possibilities for a pathogenetic treatment of this syndrome with sermion (nicergoline). Twenty-two patients, aged 21-71 years (a half of them were outpatients and another half were inpatients), were treated with sermion. Treatment duration ranged from 2 to 6 months. The positive effect of sermion on the most frequent clinical symptoms of the vertebral artery syndrome, including headache, vertigo and persistent or sudden increase in the blood pressure, was noted. The long-term treatment with sermion revealed a significant improvement in patient's quality of life measured with SF-36. The treatment was effective in any variant of vertebral artery syndrome regardless of its causes.

MATERIALS
Product Number
Brand
Product Description

Supelco
Nicergoline, analytical standard, for drug analysis
Nicergoline for peak identification, European Pharmacopoeia (EP) Reference Standard
Nicergoline for system suitability, European Pharmacopoeia (EP) Reference Standard