Phytochemical investigations of a MeOH extract obtained from the heartwoods of the Litsea glutinosa (Lauraceae) led to the isolation and characterization of four new butenolides, (3R,4S,5S)-2-hexadecyl-3-hydroxy-4-methylbutanolide 1, litsealactone C (2), and litsealactone D (4), litsealactone G (5), and a new benzoic acid derivative named eusmoside C (3). The structures of these compounds were elucidated on the basis of spectral studies.