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  • Dual infection by streptococcus and atypical mycobacteria following Ahmed glaucoma valve surgery.

Dual infection by streptococcus and atypical mycobacteria following Ahmed glaucoma valve surgery.

Seminars in ophthalmology (2013-05-01)
Aparna Rao, Batriti Wallang, Tapas Ranjan Padhy, Ruchi Mittal, Savitri Sharma
ABSTRACT

To report a case of late postoperative endophthalmitis caused by Streptococcus pneumoniae and conjunctival necrosis by Streptococcus pneumoniae and Mycobacterium fortuitum following Ahmed glaucoma valve (AGV) surgery in a young patient. Case report of a 13-year-old boy with purulent exudates and extensive conjunctival necrosis two months following amniotic membrane graft and conjunctival closure (for conjunctival retraction post AGV for secondary glaucoma). The conjunctiva showed extensive necrosis causing exposure of the tube and plate associated with frank exudates in the area adjoining the plate and anterior chamber mandating explantation of the plate along with intravitreal antibiotics. The vitreous aspirate grew Streptococcus pneumoniae while Streptococcus pneumoniae with Mycobacterium fortuitum was isolated from the explanted plate. Despite adequate control of infection following surgery, the final visual outcome was poor owing to disc pallor. Conjunctival necrosis and retraction post-AGV can cause late postoperative co-infections by fulminant and slow-growing organisms. A close follow-up is therefore essential in these cases to prevent sight-threatening complications.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Amikacin hydrate, aminoglycoside antibiotic
Amikacin for system suitability, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
Amikacin disulfate salt, potency: 674-786 μg per mg (as amikacin base)
Amikacin sulfate, European Pharmacopoeia (EP) Reference Standard
Amikacin, European Pharmacopoeia (EP) Reference Standard