The concentration of p- and m-tyramine in the rat mesolimbic system: its regional distribution and effect of monoamine oxidase inhibition.

The concentrations of p-tyramine and m-tyramine have been determined in 6 brain areas from the mesolimbic system by a specific and sensitive mass spectrometric technique. p- and m-Tyramine are unevenly distributed amongst these nuclei. The highest concentrations of p-tyramine were measured in the olfactory tubercle followed by the nucleus accumbens and septal nuclei while for m-tyramine the concentrations decreased in the following order: olfactory tubercle, nucleus accumbens, amygdala, septal nuclei and nucleus tractus diagonalis.