- Hydroxylase cofactor activity in cerebrospinal fluid of normal subjects and patients with Parkinson's disease.
Hydroxylase cofactor activity in cerebrospinal fluid of normal subjects and patients with Parkinson's disease.
Science (New York, N.Y.) (1979-05-11)
W Lovenberg, R A Levine, D S Robinson, M Ebert, A C Williams, D B Calne
PMID432666
ABSTRACT
A method for measuring hydroxylase cofactor activity in human cerebrospinal fluid is described. The hydroxylase cofactor content of cerebrsopinal fluid from Parkinsonian patients is approximately 50 percent that of normal subjects. A significant correlation between hydroxylase cofactor and the concentration of homovanillic acid in the cerebrospinal fluid was observed.
MATERIALS