- Vitamin D conversion by sarcoid lymph node homogenate.
Vitamin D conversion by sarcoid lymph node homogenate.
Annals of internal medicine (1984-01-01)
R S Mason, T Frankel, Y L Chan, D Lissner, S Posen
PMID6546329
ABSTRACT
Recent studies suggest that hypercalcemia of sarcoidosis is due to high blood concentrations of calcitriol and that this compound may be synthesized at an extra-renal site. We report that sarcoid lymph node homogenate metabolized calcifediol to a substance indistinguishable from calcitriol, whereas six nonsarcoid lymph nodes failed to produce this compound.
MATERIALS
Product Number
Brand
Product Description
Calcitriol, European Pharmacopoeia (EP) Reference Standard
Supelco
1α,25-Dihydroxyvitamin D3 solution, 5 μg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®