- [Antidepressant treatment associated hyponatremia -- case report].
[Antidepressant treatment associated hyponatremia -- case report].
Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology (2013-10-11)
Zsófia Bognár, Gabriella Vonyik, Gábor Gazdag
PMID24108183
ABSTRACT
Hyponatremia is a potential side-effect of antidepressants that was observed most frequently in connection with compounds acting on the serotonin system. Risk of hyponatremia was found to be higher in the elderly. Authors report a case of a 65-year old male patient who was treated with venlafaxine-mirtazapine combination for recurrent depression. Severe hyponatremia, requiring intensive care, emerged in connection with the treatment. The authors emphasize the importance of the regular checking of serum sodium levels during antidepressant treatment, especially in elderly patients.
MATERIALS
Product Number
Brand
Product Description
Supelco
Venlafaxine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
Supelco
Mirtazapine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
Venlafaxine for system suitability, European Pharmacopoeia (EP) Reference Standard
Venlafaxine hydrochloride, European Pharmacopoeia (EP) Reference Standard