- Going mobile: AMPA receptors move synapse to synapse in vivo.
Going mobile: AMPA receptors move synapse to synapse in vivo.
Neuron (2013-12-24)
Christopher Rongo
PMID24360537
ABSTRACT
Plasticity models invoke the synaptic delivery of AMPARs, yet we know little about how receptors move in vivo. In this issue of Neuron, Hoerndli et al. (2013) show that lateral diffusion and kinesin-mediated transport move AMPARs between synapses in vivo.
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Adenosine 5′-Triphosphatase from porcine cerebral cortex, lyophilized powder, ≥0.3 units/mg protein, pH 7.8