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  • Morierinin: a new cytotoxic cucurbitacin from the leaves of Morierina montana Vieill.

Morierinin: a new cytotoxic cucurbitacin from the leaves of Morierina montana Vieill.

Natural product research (2003-06-26)
Marc Litaudon, Christianne Gaspard, Thierry Sévenet
ABSTRACT

An extract of the leaves of Morierina montana collected in New Caledonia was found to be cytotoxic for KB cells. A bioassay-guided fractionation procedure led to the isolation of a series of cucurbitacins of which one, morierinin (1), is new. The isolation and structure elucidation of 1 are described.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Cucurbitacin E, ≥95% (HPLC)