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Cobalt sensitization and dermatitis: considerations for the clinician.

Cobalt sensitization and dermatitis: considerations for the clinician.

Dermatitis : contact, atopic, occupational, drug (2012-09-27)

Jacob P Thyssen

ABSTRACT

This clinical review article presents clinical and scientific data on cobalt sensitization and dermatitis. It is concluded that cobalt despite being a strong sensitizer and a prevalent contact allergen to come up on patch testing should be regarded as a very complex metal to test with. Exposure data together with clinical data from metal workers heavily exposed to cobalt suggest that patch-test reactions are sometimes false positive and that patch testers should carefully evaluate their clinical relevance.

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

Cobalt, foil, thickness 0.1 mm, 99.95% trace metals basis

Sigma-Aldrich

Cobalt, rod, diam. 5.0 mm, 99.95% trace metals basis

Sigma-Aldrich

Cobalt, foil, thickness 1.0 mm, 99.95% trace metals basis

Sigma-Aldrich

Cobalt, foil, thickness 0.1 mm, ≥99.99%

Sigma-Aldrich

Cobalt, wire, diam. 1.0 mm, 99.995% trace metals basis

Sigma-Aldrich

Cobalt, granular, 99.99% trace metals basis

Cobalt, foil, 25x25mm, thickness 1.0mm, as rolled, 99.99+%

Cobalt, foil, not light tested, 50x50mm, thickness 0.025mm, 99.9%

Sigma-Aldrich

Cobalt, pieces, 99.5% trace metals basis

Sigma-Aldrich

Cobalt, Carbon coated magnetic, nanopowder, <50 nm particle size (TEM), ≥99%

Cobalt, wire reel, 0.5m, diameter 0.5mm, hard, 99.99+%

Sigma-Aldrich

Cobalt, powder, 2 μm particle size, 99.8% trace metals basis

Cobalt, wire reel, 2m, diameter 0.05mm, hard, 99.9%

Cobalt, foil, not light tested, 25x25mm, thickness 0.008mm, 99.9%

Cobalt, foil, 8mm disks, thickness 0.025mm, 99.9%

Cobalt, foil, 8mm disks, thickness 0.007mm, 99.9%

Cobalt, foil, 8mm disks, thickness 0.05mm, as rolled, 99.99+%

Cobalt, foil, 6mm disks, thickness 0.006mm, 99.9%

Cobalt, foil, not light tested, 25x25mm, thickness 0.005mm, 99.9%

Cobalt, foil, not light tested, 50x50mm, thickness 0.0125mm, 99.9%

Cobalt, foil, 4mm disks, thickness 0.125mm, annealed, 99.9%

Cobalt, foil, 4mm disks, thickness 0.025mm, 99.9%

Cobalt, microfoil, disks, 10mm, thinness 0.25μm, specific density 222μg/cm², permanent mylar 3.5μm support, 99.9%

Cobalt, foil, 6mm disks, thickness 0.007mm, 99.9%

Cobalt, foil, 8mm disks, thickness 0.25mm, as rolled, 99.9%

Cobalt, foil, 8mm disks, thickness 0.05mm, as rolled, 99.9%

Cobalt, foil, light tested, 25x25mm, thickness 0.015mm, 99.9%

Cobalt, wire reel, 0.025m, diameter 2.0mm, hard, 99.99+%

Cobalt, foil, light tested, 100x100mm, thickness 0.05mm, as rolled, 99.99+%

Cobalt, foil, 6mm disks, thickness 0.015mm, 99.9%