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  • Gold nanoparticles and fluorescently-labelled DNA as a platform for biological sensing.

Gold nanoparticles and fluorescently-labelled DNA as a platform for biological sensing.

Nanoscale (2013-08-29)
Amelie Heuer-Jungemann, Pascal K Harimech, Tom Brown, Antonios G Kanaras
ABSTRACT

In the past decade gold nanoparticle-nucleic acid conjugates became progressively important for biomedical applications. Fluorophores attached to nucleic acid-gold nanoparticle conjugates have opened up a new era of biological sensing. The most promising advancement in this field was the invention of the so-called 'nano-flare' systems. These systems are capable of detecting specific endocellular targets such as mRNAs, microRNAs or small molecules in real time. In this minireview, we discuss the current progress in the field of DNA-nanoparticles as sensors, their properties, stability, cellular uptake and cytotoxicity.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Gold, powder, <45 μm, 99.99% trace metals basis
Gold, rod, 6mm, diameter 6.0mm, as drawn, 99.95%
Gold, insulated wire, 0.5m, conductor diameter 0.125mm, insulation thickness 0.016mm, PTFE (polytetrafluoroethylene) insulation, 99.99%
Gold, microfoil, disks, 10mm, thinness 0.1μm, specific density 204.1μg/cm2, permanent mylar 3.5μm support, 99.99+%
Gold, tube, 100mm, outside diameter 3.0mm, inside diameter 2.8mm, wall thickness 0.10mm, as drawn, 99.95%
Gold, tube, 100mm, outside diameter 1.0mm, inside diameter 0.5mm, wall thickness 0.25mm, as drawn, 99.95%
Gold, microfoil, disks, 10mm, thinness 0.5μm, specific density 966μg/cm2, permanent mylar 3.5μm support, 99.99+%
Gold, rod, 10mm, diameter 6.0mm, as drawn, 99.95%
Gold, tube, 50mm, outside diameter 1.0mm, inside diameter 0.5mm, wall thickness 0.25mm, as drawn, 99.95%
Gold, rod, 50mm, diameter 3.0mm, as drawn, 99.95%
Gold, tube, 200mm, outside diameter 2.0mm, inside diameter 1.8mm, wall thickness 0.1mm, as drawn, 99.95%
Gold, rod, 25mm, diameter 4.0mm, as drawn, 99.95%
Gold, tube, 100mm, outside diameter 1.60mm, inside diameter 0.6mm, wall thickness 0.5mm, as drawn, 99.95%
Gold, tube, 200mm, outside diameter 1.0mm, inside diameter 0.5mm, wall thickness 0.25mm, as drawn, 99.95%
Gold, tube, 100mm, outside diameter 10.0mm, inside diameter 9.7mm, wall thickness 0.15mm, as drawn, 99.95%
Gold, tube, 50mm, outside diameter 8mm, inside diameter 7.8mm, wall thickness 0.1mm, as drawn, 99.95%
Gold, insulated wire, 0.5m, conductor diameter 0.125mm, insulation thickness 0.014mm, polyester insulation, 99.99%
Gold, insulated wire, 5m, conductor diameter 0.05mm, insulation thickness 0.007mm, polyester insulation, 99.99%
Gold, microleaf disks, 10mm, thinness 0.5μm, specific density 966μg/cm2, removable support, 99.99+%
Gold, insulated wire, 0.5m, conductor diameter 0.025mm, insulation thickness 0.005mm, polyester insulation, 99.99%
Gold, insulated wire, 1m, conductor diameter 0.05mm, insulation thickness 0.007mm, polyester insulation, 99.99%
Gold, microfoil, disks, 10mm, thinness 0.01μm, specific density 20.7μg/cm2, permanent mylar 3.5μm support, 99.99+%
Gold, insulated wire, 1m, conductor diameter 0.05mm, insulation thickness 0.007mm, polyimide insulation, 99.99%
Gold, insulated wire, 2m, conductor diameter 0.075mm, insulation thickness 0.012mm, PTFE (polytetrafluoroethylene) insulation, 99.99%
Gold, rod, 100mm, diameter 2.0mm, as drawn, 99.95%
Gold, insulated wire, 1m, conductor diameter 0.075mm, insulation thickness 0.012mm, PTFE (polytetrafluoroethylene) insulation, 99.99%
Gold, insulated wire, 2m, conductor diameter 0.125mm, insulation thickness 0.014mm, polyester insulation, 99.99%
Gold, insulated wire, 0.5m, conductor diameter 0.075mm, insulation thickness 0.012mm, PTFE (polytetrafluoroethylene) insulation, 99.99%
Gold, tube, 200mm, outside diameter 2.0mm, inside diameter 1.7mm, wall thickness 0.15mm, as drawn, 99.95%
Gold, microfoil, disks, 10mm, thinness 0.05μm, specific density 101.3μg/cm2, permanent mylar 3.5μm support, 99.99+%