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  • [Influence of morphine and reserpine on the experimental effect of electrostimulation of biologically active points].

[Influence of morphine and reserpine on the experimental effect of electrostimulation of biologically active points].

Farmakologiia i toksikologiia (1980-03-01)
V V Iasnetsov, M V Komendantova
ABSTRACT

In experiments on unanesthetized cats, electric stimulation of biologically active points (BAP) led to a prolonged facilitation of the amplitude of brain cortex evoked potentials. Morphine (2--2.5 mg/kg) produced unidirectional changes (with respect to electric stimulation) in the electrophysiological indices. Reserpine (5 mg/kg) shortened the period of the effect induced by electric stimulation of BAP during complete depletion of the brain monoamine pool. It is suggested that variation in the balance of brain biogenic amines is of certain importance for, rather than determines the realization of the effect of BAP electric stimulation.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Reserpine, crystallized, ≥99.0% (HPLC)