Merck
CN

Chemical modification of neamine.

Carbohydrate research (1977-02-01)
T Suami, S Nishiyama, Y Ishikawa, S Katsura
PMID404040
ABSTRACT

The aminocyclitol antibiotic neamine has been modified chemically by removing one or two hydroxyl groups from the 2-deoxystreptamine moiety to give 5- and 6- deoxyneamines (5 and 10), as well as 5,6-dideoxyneamine (15). Their antimicrobial activities were determined against several microorganisms, including kanamycin-resistant strains.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Selenium, powder, −100 mesh, 99.99% trace metals basis
Sigma-Aldrich
Sodium fluoride, anhydrous, powder, 99.99% trace metals basis
Sigma-Aldrich
3-Methyl-2(5H)-furanone, technical grade, 90%
Sigma-Aldrich
Silica, mesoporous MCM-48, <15 μm particle size, pore size 3 nm, thiol functionalized
Sigma-Aldrich
Triethylene glycol monomethyl ether, purum, ≥97.0% (GC)
Sigma-Aldrich
Tumor Necrosis Factor-α from rat, TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture
Sigma-Aldrich
Orcinol, 97%
Sigma-Aldrich
Poly[(phenyl glycidyl ether)-co-formaldehyde], average Mn ~345