Merck
CN
  • Management of vascular complications following transcatheter aortic valve implantation.

Management of vascular complications following transcatheter aortic valve implantation.

Archives of cardiovascular diseases (2015-06-16)
Nils Perrin, Christoph Ellenberger, Marc Licker, Anne-Lise Hachulla, Mustafa Cikirikcioglu, Angela Frei, Marco Roffi, Stéphane Noble
ABSTRACT

Vascular complications (VCs) after transcatheter aortic valve implantation (TAVI) are frequent and their management is challenging. To report the incidence, predictors and management of VCs following percutaneous transfemoral TAVI (TF-TAVI) at a single centre. We analyzed 102 consecutive patients who underwent percutaneous TF-TAVI between August 2008 and December 2013. All endpoints were evaluated at 30 days and 6 months according to Valve Academic Research Consortium-2 criteria. VC percutaneous treatment success was defined as residual stenosis<30%, absence of blood extravasation and absence of surgical or repeat endovascular intervention at 30 days. Twenty-two patients (22%) experienced VCs, including five patients (5%) with major VCs. Mortality at 30 days was significantly higher in patients with major VCs than in patients without major VCs (60% vs 3%; P=0.001). Patients with VCs had more life-threatening or major bleeding (23% vs 5%; P=0.02), but no difference in terms of need for blood transfusion was observed. Endovascular treatment was used in 13 of 22 patients with VCs (59%) and was successful in 11 of these 13 patients (85%). Primary surgical repair was necessary in only 1/22 (5%) patients, for a common femoral artery pseudoaneurysm 2 weeks after the TAVI procedure. VCs following TF-TAVI are frequent. Major but not minor VCs are associated with increased mortality. Percutaneous management of VCs is feasible and safe, and surgery is rarely needed.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Poly(tetrafluoroethylene), powder, >40 μm particle size
Sigma-Aldrich
Poly(tetrafluoroethylene), powder (free-flowing), 1 μm particle size
Sigma-Aldrich
Poly(tetrafluoroethylene), powder, 200 μm particle size
Sigma-Aldrich
Poly(tetrafluoroethylene), powder, 35 μm particle size
Sigma-Aldrich
Poly(tetrafluoroethylene), powder (free-flowing), ≤12 μm particle size
Sigma-Aldrich
Poly(tetrafluoroethylene), beads
Sigma-Aldrich
Poly(tetrafluoroethylene), powder, ≥350 μm particle size