Merck
CN

1',2'-seco-dideoxynucleosides as potential anti-HIV agents.

Journal of medicinal chemistry (1989-01-01)
E Abushanab, M S Sarma
ABSTRACT

1',2'-seco-2',3'-Dideoxycytidine (12), -guanosine (14), -adenosine (16), and -inosine (18) were prepared from (R)-benzylglycidol as potential anti-HIV agents. When compared to ddAdo in protecting ATH8 cells, they were found to be inactive.