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  • In vitro cytotoxic and genotoxic evaluation of peptides used in nuclear medicine (DOTATATE and Ubiquicidin

In vitro cytotoxic and genotoxic evaluation of peptides used in nuclear medicine (DOTATATE and Ubiquicidin

Cytotechnology (2016-10-01)
Ivette Zegarra Ocampo, Priscila de Queiroz Souza Passos, Luma Ramirez de Carvalho, Camila Ayala Lira da Cruz, Natália Mencacci Esteves-Pedro, Fabiana Medeiros da Silva, Olga Zazuco Higa, Luiz Alberto Pereira Dias, Kayo Okazaki, Daniel Perez Vieira
ABSTRACT

Micronucleus (MN) assay constitutes a valuable surrogate to the chromosome aberration technique for in vitro testing of the genotoxicity of substances. As test substances, two peptidic compounds (DOTATATE and Ubiquicidin

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Acridine Orange hydrochloride solution, 10 mg/mL in H2O, ≥95.0% (HPLC)
Sigma-Aldrich
Cytochalasin B from Drechslera dematioidea, ≥98% (HPLC), powder