- Bacterial Peptide Deformylase Inhibition of Tetrazole-Substituted Biaryl Acid Analogs: Synthesis, Biological Evaluations, and Molecular Docking Study.
Bacterial Peptide Deformylase Inhibition of Tetrazole-Substituted Biaryl Acid Analogs: Synthesis, Biological Evaluations, and Molecular Docking Study.
Archiv der Pharmazie (2016-11-20)
Firoz A Kalam Khan, Rajendra H Patil, Manjiri Patil, Rohidas Arote, Devanand B Shinde, Jaiprakash N Sangshetti
PMID27859538
ABSTRACT
The synthesis and screening of tetrazole-substituted biaryl acid analogs 7a-l as bacterial peptide deformylase (PDF) enzyme inhibitors is reported. The compounds 7e (IC
MATERIALS