- Using affinity capillary electrophoresis and computational models for binding studies of heparinoids with p-selectin and other proteins.
Using affinity capillary electrophoresis and computational models for binding studies of heparinoids with p-selectin and other proteins.
Electrophoresis (2017-03-04)
Mona Mozafari, Shantheya Balasupramaniam, Lutz Preu, Sami El Deeb, Christian G Reiter, Hermann Wätzig
PMID28256735
ABSTRACT
A fast and precise affinity capillary electrophoresis (ACE) method has been developed and applied for the investigation of the binding interactions between P-selectin and heparinoids as potential P-selectin inhibitors in the presence and absence of calcium ions. Furthermore, model proteins and vitronectin were used to appraise the binding behavior of P-selectin. The normalized mobility ratios (∆R/R
MATERIALS
Product Number
Brand
Product Description