- Lysophosphatidylcholine elicits intracellular calcium signaling in a GPR55-dependent manner.
Lysophosphatidylcholine elicits intracellular calcium signaling in a GPR55-dependent manner.
Biochemical and biophysical research communications (2017-05-30)
Anna Drzazga, Agata Sowinska, Agnieszka Krzeminska, Przemysław Rytczak, Maria Koziolkiewicz, Edyta Gendaszewska-Darmach
PMID28552522
ABSTRACT
The GPR55 signaling is fertile ground for drug discovery, however despite considerable research progress during the past 10 years, many open questions remain. The GPR55 pharmacology remains controversial, as many ligands have been reported with inconsistent results. Here, we show that various molecular species of lysophosphatidylcholine (LPC) elicit intracellular Ca
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