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  • Targeted inactivation of copper transporter Atp7b in hepatocytes causes liver steatosis and obesity in mice.

Targeted inactivation of copper transporter Atp7b in hepatocytes causes liver steatosis and obesity in mice.

American journal of physiology. Gastrointestinal and liver physiology (2017-04-22)
Abigael Muchenditsi, Haojun Yang, James P Hamilton, Lahari Koganti, Franck Housseau, Lisa Aronov, Hongni Fan, Hannah Pierson, Ashima Bhattacharjee, Robert Murphy, Cynthia Sears, James Potter, Clavia R Wooton-Kee, Svetlana Lutsenko
ABSTRACT

Copper-transporting ATPase 2 (ATP7B) is essential for mammalian copper homeostasis. Mutations in