- CXCR3/CXCL10 Axis Regulates Neutrophil-NK Cell Cross-Talk Determining the Severity of Experimental Osteoarthritis.
CXCR3/CXCL10 Axis Regulates Neutrophil-NK Cell Cross-Talk Determining the Severity of Experimental Osteoarthritis.
Journal of immunology (Baltimore, Md. : 1950) (2017-01-22)
Giorgia Benigni, Petya Dimitrova, Fabrizio Antonangeli, Emilio Sanseviero, Viktoriya Milanova, Arjen Blom, Peter van Lent, Stefania Morrone, Angela Santoni, Giovanni Bernardini
PMID28108560
ABSTRACT
Several immune cell populations are involved in cartilage damage, bone erosion, and resorption processes during osteoarthritis. The purpose of this study was to investigate the role of NK cells in the pathogenesis of experimental osteoarthritis and whether and how neutrophils can regulate their synovial localization in the disease. Experimental osteoarthritis was elicited by intra-articular injection of collagenase in wild type and
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