- Uptake of perfluorooctanoic acid by Caco-2 cells: Involvement of organic anion transporting polypeptides.
Uptake of perfluorooctanoic acid by Caco-2 cells: Involvement of organic anion transporting polypeptides.
Toxicology letters (2017-05-30)
Osamu Kimura, Yukiko Fujii, Koichi Haraguchi, Yoshihisa Kato, Chiho Ohta, Nobuyuki Koga, Tetsuya Endo
PMID28552774
ABSTRACT
The mechanism underlying the intestinal absorption of perfluorooctanoic acid (PFOA) was investigated using Caco-2 cells. The uptake of PFOA from the apical membrane of Caco-2 cells was fast, and pH, temperature, and concentration dependent, but Na