- Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis.
Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis.
Kidney international (2017-04-08)
Robert A Fenton, Søren B Poulsen, Samantha de la Mora Chavez, Manoocher Soleimani, Jessica A Dominguez Rieg, Timo Rieg
PMID28385297
ABSTRACT
The sodium/proton exchanger isoform 3 (NHE3) is expressed in the intestine and the kidney, where it facilitates sodium (re)absorption and proton secretion. The importance of NHE3 in the kidney for sodium chloride homeostasis, relative to the intestine, is unknown. Constitutive tubule-specific NHE3 knockout mice (NHE3
MATERIALS