- Two new sesquiterpene lactone glycosides from Cnicus benedictus.
Two new sesquiterpene lactone glycosides from Cnicus benedictus.
Natural product research (2017-03-14)
Ying Peng, Yuqing Jian, Ali Zulfiqar, Bin Li, Kaiqiang Zhang, Fei Long, Caiyun Peng, Xiong Cai, Ikhlas A Khan, Wei Wang
PMID28287272
ABSTRACT
Two new sesquiterpene lactone glycosides, namely melitensin 15-O-β-D-glucoside (1) and 11β,13-dihydrosalonitenolide 15-O-β-D-glucoside (2), along with eight known compounds (3-10) were isolated from the aerial part of Cnicus benedictus L. Their structures were elucidated from analyses of extensive spectroscopic data. Compounds 1-6 all possessed an α-methyl-γ-lactone moiety. Moreover, compound 5 exhibited moderate activity against the growth of Aspergillus fumigatus, with IC
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