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  • Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.

Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.

Biochemical and biophysical research communications (2017-07-27)
Jihyun Lee, Goowon Yang, Young-Joo Kim, Quynh Hoa Tran, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha
ABSTRACT

Persistent oxidative stress is recognized as a major cause of many pathological conditions as well as ageing. However, most clinical trials of dietary antioxidants have failed to produce successful outcomes in treating oxidative stress-induced diseases. Molecular hydrogen (H

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Dorsomorphin, ≥98% (HPLC)
Sigma-Aldrich
DL-Glyceraldehyde 3-phosphate solution, 45-55 mg/mL in H2O
Sigma-Aldrich
Tetramethylrhodamine methyl ester perchlorate, ≥95%