Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity.

Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity.

Frontiers in pharmacology (2017-11-23)

Huan-Yu Guan, Peng-Fei Li, Xiao-Ming Wang, Jia-Jing Yue, Yang He, Xiao-Mei Luo, Mei-Feng Su, Shang-Gao Liao, Yue Shi

ABSTRACT

Shengjiang Xiexin decoction (SXD), a classic traditional Chinese medical formula chronicled in

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

DL-Glyceraldehyde 3-phosphate solution, 45-55 mg/mL in H₂O

Sigma-Aldrich

8-Cyclopentyl-1,3-dimethylxanthine, ≥98% (HPLC), powder

Sigma-Aldrich

Uridine 5′-diphosphoglucuronic acid ammonium salt, 98-100%