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  • Nitric oxide mediated inhibition of antigen presentation from DCs to CD4

Nitric oxide mediated inhibition of antigen presentation from DCs to CD4

Scientific reports (2017-11-15)
Joseph Markowitz, Jiang Wang, Zach Vangundy, Jia You, Vedat Yildiz, Lianbo Yu, Isaac P Foote, Owen E Branson, Andrew R Stiff, Taylor R Brooks, Brandon Biesiadecki, Thomas Olencki, Susheela Tridandapani, Michael A Freitas, Tracey Papenfuss, Mitch A Phelps, William E Carson
ABSTRACT

Myeloid derived suppressor cells (MDSC) produce nitric oxide (NO) and inhibit dendritic cell (DC) immune responses in cancer. DCs present cancer cell antigens to CD4

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
S-Nitroso-N-acetyl-DL-penicillamine, ≥97%, powder