- MicroRNA-182 targets protein phosphatase 1 regulatory inhibitor subunit 1C in glioblastoma.
MicroRNA-182 targets protein phosphatase 1 regulatory inhibitor subunit 1C in glioblastoma.
Oncotarget (2018-02-01)
Liqiang Liu, Xiaowei Zhang, Chengrui Nan, Zongmao Zhao, Shucheng Ma, Wenhua Li, Hongchao Hu, Zhaohui Liang
PMID29383111
ABSTRACT
Glioblastoma (GBM) is an incurable cancer, with mean post-diagnosis survival time of 14-16 months. Metagenomic analysis by The Cancer Genome Atlas (TCGA) program has identified microRNA-182-5p (miR-182-5p or miR-182) as the only miRNA associated with favorable disease prognosis and temozolomide (TMZ) susceptibility. Previous reports have indicated that miR-182 down regulates expression of
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