血型鉴定
血型鉴定（又称血型分型）是一种通过检测红细胞(RBC)表面抗原对血液进行分类的过程。准确测定献血者和患者的血型在抢救时对于血液及其成分输送以及器官和组织移植的安全性至关重要。因此，血型鉴定要求使用监管严厉、标准化且具有血型特异性的试剂或设备来检测血样。
国际输血协会(ISBT)批准了39种主要的人类血型系统用于鉴定常见和稀有的变异型血型，其中最常见当属ABO和Rh血型系统。血型鉴定的基本原理是观察可致红细胞凝集或结块的抗原抗体简单反应。
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国际输血协会(ISBT)批准了39种主要的人类血型系统用于鉴定常见和稀有的变异型血型，其中最常见当属ABO和Rh血型系统。血型鉴定的基本原理是观察可致红细胞凝集或结块的抗原抗体简单反应。
ABO血型系统一般通过个体红细胞与抗A、抗B和抗AB抗血清的凝集反应鉴定个体表型（正定型）。反应未发生凝集表明不存在特异性抗原，则结果为阴性。而通过个体血清与标准A型和B型红细胞悬液的反应则可鉴定成人血样的ABO血型（反定型）。
由于鉴定结果起到治疗性而非诊断性作用，因而任何市场对血型鉴定试剂和设备的监管都格外严厉。鉴定结果决定了向患者提供何种血液、血制品或移植组织。严厉的监管使得血型鉴定试剂和设备的开发和生产高度依赖于关键抗体原料、辅助化学品和组分的质量、一致性和可靠性。
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专题文章
- Case Study: OEM Blood Typing
A Blood Typing company was going through the process of expanding its portfolio of blood typing platform assays to further penetrate the market.
- Brochure: Blood Typing Monoclonal Antibodies FFMU
Merck is one of the leading providers of monoclonal antibodies to the blood typing market. Our large portfolio of standardized antibody intermediates for further manufacturing use allows manufacturers to create and manufacture a wide variety of blood typing reagents and devices.
- Brochure: BIOSCOT® Blood Typing Monoclonal Reagents
The BIOSCOT® name is globally synonymous with quality & Merck is one of the leading providers of monoclonal antibodies for the blood typing market. We offer the largest portfolio of human IgM monoclonal antibodies available today.
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