BCL2A1
BCL2-related protein A1
别名:
ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1
物种:
Human BCL2A1 (597), Rat Bcl2a1 (170929), cow BCL2A1 (282151), chicken BCL2A1 (395673), dog BCL2A1 (488770), naked mole-rat Bcl2a1 (101702935), domestic cat BCL2A1 (768283), sheep BCL2A1 (101114560), domestic cat BCL2A1 (101086480), domestic guinea pig Bcl2a1 (100732983)
UniProtKB ID:
基因ID:
- Human(597) Summary: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Rat(170929) BCL2-related protein A1
- cow(282151) BCL2-related protein A1
- chicken(395673) BCL2-related protein A1
- dog(488770) BCL2-related protein A1
- naked mole-rat(101702935) BCL2-related protein A1
- domestic cat(768283) BCL2-related protein A1
- sheep(101114560) BCL2-related protein A1
- domestic cat(101086480) BCL2-related protein A1
- domestic guinea pig(100732983) BCL2-related protein A1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
产品编号
说明
物种反应性
应用
Anti BCL2 related protein A1 Antibody, clone 23GB4820, Rabbit Monoclonal, clone 23GB4820, recombinant rabbit monoclonal, expressed in HEK293 cells,
物种反应性
human
应用
flow cytometry
western blot
western blot
Anti-BCL2A1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-BCL2A1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, canine, human, pig
应用
ELISA
western blot
western blot
Anti-BCL2A1/BFL-1 Antibody, from rabbit, purified by affinity chromatography,
物种反应性
camelidae, bat, bovine, chimpanzee, human
应用
immunohistochemistry
western blot
western blot
Anti-BFL-1 Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
产品编号
说明
物种