Merck
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CDKN1B

cyclin-dependent kinase inhibitor 1B (p27, Kip1)

别名:
CDKN4, KIP1, MEN1B, MEN4, P27KIP1
物种:
Human CDKN1B (1027), Mouse Cdkn1b (12576), Rat Cdkn1b (83571), chicken CDKN1B (769872), chicken CDKN1B (374106), dog CDKN1B (403429), domestic cat CDKN1B (493958), Domestic Rabbit CDKN1B (100009037), cow CDKN1B (512613), sheep CDKN1B (100127219) ...展开
UniProtKB ID:
P46527, Q16307, Q5U0H2, Q9BUS6
基因ID:
  • Human(1027) Summary: This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq, Jul 2008]
  • Mouse(12576) cyclin-dependent kinase inhibitor 1B
  • Rat(83571) cyclin-dependent kinase inhibitor 1B
  • chicken(769872) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • chicken(374106) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • dog(403429) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • domestic cat(493958) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • Domestic Rabbit(100009037) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • cow(512613) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • sheep(100127219) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • naked mole-rat(101698721) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • domestic guinea pig(100729359) cyclin-dependent kinase inhibitor 1B (p27, Kip1)

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Antibodies

货号
说明
物种反应性
应用
06-996
Anti-phospho-Kip1 (Thr187) Antibody, Upstate®, from rabbit,
物种反应性
human, mouse, rat
应用
western blot
06-445
抗Kip1（p27）抗体, Upstate®, from rabbit,
物种反应性
human, rabbit, rat
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB4504200
Anti-phospho-p27 Kip1 (pThr198) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
SAB4500068
Anti-p27 KIP1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
07-500
Anti-p47-phox (mouse) Antibody, Upstate®, from rabbit,
物种反应性
mouse
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
R7772
核抑制剂, ≥98% (TLC),
物种
human, mouse, rat
O0886
奥罗莫星, ≥98% (HPLC),
物种
human, rat

Proteins

货号
说明
物种
SRP5109
p27KIP1, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
23-024-M
p27 Protein complex, activated, 10 µg, Activated complex of three (3) full length, recombinant human proteins: p27, Cyclin E1, & CDK2. Phosphorylated in vitro using CDK2/Cyclin E1. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.,
物种
human

esiRNA

货号
说明
物种
EHU025821
MISSION® esiRNA, targeting human CDKN1B,
物种
human
EMU028461
MISSION® esiRNA, targeting mouse Cdkn1b,
物种
mouse