跳转至内容
Merck
CN

CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

别名:
ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
物种:
Human CHRNA1 (1134), Mouse Chrna1 (11435), Rat Chrna1 (79557), dog CHRNA1 (403757), domestic guinea pig Chrna1 (100729588), cow CHRNA1 (338070), chicken CHRNA1 (395608), sheep CHRNA1 (101110120), Zebrafish chrna1 (30725), naked mole-rat Chrna1 (101715747)
UniProtKB ID:
P02708, B4DRV6, D3DPE8
基因ID:
  • Human(1134) Summary: The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2012]
  • Mouse(11435) cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
  • Rat(79557) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • dog(403757) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • domestic guinea pig(100729588) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • cow(338070) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • chicken(395608) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • sheep(101110120) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • Zebrafish(30725) cholinergic receptor, nicotinic, alpha polypeptide 1
  • naked mole-rat(101715747) cholinergic receptor, nicotinic, alpha 1 (muscle)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Product Number
说明
物种
396966
十烃溴铵, Ion-Pair reagent, ≥99%,
物种
human
N5511
(−)-尼古丁 溶液, 1.0 mg/mL, analytical standard, for drug analysis,
物种
human, mouse, rat
D1260
十烃溴铵, crystalline,
物种
human
D5891
1,1-二甲基-4-苯基哌嗪碘化物, ≥98% (TLC or titration),
物种
human, rat

Small Molecule - Antagonist

Product Number
说明
物种
472328
1-辛醇, ACS reagent, ≥99%,
物种
mouse
293245
1-辛醇, suitable for HPLC, ≥99%,
物种
mouse
112615
1-辛醇, ReagentPlus®, 99%,
物种
mouse
297887
1-辛醇, anhydrous, ≥99%,
物种
mouse
W280003
1-辛醇, ≥98%, FCC, FG,
物种
mouse

Antibodies

Product Number
说明
物种反应性
应用
MABN1618
Anti-Nicotinic Acetylchone Receptor alpha 1 Antibody, clone 7C8.2, clone 7C8.2, from mouse,
物种反应性
human, rat
应用
immunohistochemistry
western blot
ZRB2584
Anti-CHRNA1/ACHRA Antibody, clone 2G22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
SAB1402724
Monoclonal Anti-CHRNA1 antibody produced in mouse, clone 2G5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
AV34910
Anti-CHRNA1 (AB2) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
AV34909
Anti-CHRNA1 (AB1) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot

Small Molecule - Blocker

Product Number
说明
物种
T2265
四乙基氯化铵, ≥98% (titration),
物种
human
H0879
溴化已烷双胺, ,
物种
human
H2138
氯化六甲铵, solid (hygroscopic),
物种
human
K3375
犬尿喹啉酸, ≥98%,
物种
rat, human

Small Molecule - Mixed Agonist/Antagonist

Product Number
说明
物种
N5511
(−)-尼古丁 溶液, 1.0 mg/mL, analytical standard, for drug analysis,
物种
human, mouse, rat

esiRNA

Product Number
说明
物种
EHU061451
MISSION® esiRNA, targeting human CHRNA1,
物种
human