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Merck
CN

P2RY12

purinergic receptor P2Y, G-protein coupled, 12

别名:
ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999
物种:
UniProtKB ID:
基因ID:
  • Human(64805) Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • Mouse(70839) purinergic receptor P2Y, G-protein coupled 12
  • Rat(64803) purinergic receptor P2Y, G-protein coupled, 12
  • dog(442958) purinergic receptor P2Y, G-protein coupled, 12
  • cow(408007) purinergic receptor P2Y, G-protein coupled, 12
  • sheep(101117897) purinergic receptor P2Y, G-protein coupled, 12
  • naked mole-rat(101701294) purinergic receptor P2Y, G-protein coupled, 12
  • domestic cat(101094044) purinergic receptor P2Y, G-protein coupled, 12
  • domestic guinea pig(100720551) purinergic receptor P2Y, G-protein coupled, 12

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Small Molecule - Agonist

货号
说明
物种
尿苷 5′-(二磷酸三氢) 钠盐 来源于酿酒酵母, 95-100%,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
替格瑞洛, ≥98% (HPLC),
物种
human

Small Molecule - Antagonist

货号
说明
物种
硫酸氯吡格雷, United States Pharmacopeia (USP) Reference Standard,
物种
human
Prasugrel, ≥98% (HPLC),
物种
human
硫酸氢氯吡格雷, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
噻氯匹定 盐酸盐, analytical standard, for drug analysis,
物种
human
Prasugrel for system suitability, European Pharmacopoeia (EP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
抗-P2RY12 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
抗-P2RY12 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-P2RY12 Antibody, clone 2C12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-P2RY12 Antibody, clone 10B5.3.27, ,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-P2Y12 Receptor, from rabbit, purified by affinity chromatography,
物种反应性
human, rat
应用
immunohistochemistry
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human P2RY12,
物种
human
MISSION® esiRNA, targeting mouse P2ry12,
物种
mouse