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U4125

Sigma-Aldrich

尿苷 5′-（二磷酸三氢） 钠盐 来源于酿酒酵母

95-100%

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别名:
UDP 钠盐, Uridine 5′-(trihydrogen pyrophosphate) 钠盐
经验公式（希尔记法）:
C9H14N2O12P2 · xNa+
CAS号:
21931-53-3
分子量:
404.16 (free acid basis)
PubChem化学物质编号:
24278767
NACRES:
NA.77

检测方案

95-100%

溶解性

H2O: soluble 100 mg/mL, clear, colorless to very faintly yellow

储存温度

−20°C

SMILES string

[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)N2C=CC(=O)NC2=O

InChI

1S/C9H14N2O12P2.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3

InChI key

GFASEGWJDXDCKZ-UHFFFAOYSA-K

Gene Information

human ... LPAR4(2846) , LTB4R(1241) , P2RY1(5028) , P2RY10(27334) , P2RY11(5032) , P2RY12(64805) , P2RY13(53829) , P2RY14(9934) , P2RY2(5029) , P2RY4(5030) , P2RY5(10161) , P2RY6(5031) , P2RY8(286530)

应用

UDP已用作嘌呤能激动剂，研究其对耳蜗外沟细胞（OSC）和前庭移行细胞（VTC）吸收阳离子通量的影响 。UDP 还用于兔视网膜中核苷二磷酸酶（NDPase）活性测定 。

生化/生理作用

P2Y 受体激动剂。

特点和优势

该化合物的相关信息整理于受体分类和信号转导手册的 P2受体：P2Y G蛋白家族 页面。想要浏览手册的其他页面， 请单击此处。

制备说明

尿苷 5′-（三磷酸二氢钠）钠或 UDP 钠盐溶于水，浓度为 100 mg/mL，成为澄清、无色至微淡黄色溶液。

象形图

Health hazard
GHS08

警示用语：

Warning

危险声明

H371

危险分类

STOT SE 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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J H Lee et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(23), 9168-9174 (2001-11-22)
Cochlear outer sulcus cells (OSC) and vestibular transitional cells (VTC) are part of the parasensory epithelium in the inner ear and are located in homologous positions between the sensory hair cells and the cation secretory epithelial cells in the cochlea
J Schnitzer
The Journal of comparative neurology, 282(2), 249-263 (1989-04-08)
Enzyme-histochemical methods for thiamine pyrophosphatase (TPPase) and nucleoside diphosphatase (NDPase) were applied to wholemounted rabbit retinae to demonstrate the shape and distribution of microglial cells in early postnatal and adult animals. At birth, microglial cells were already present in the
Markie O Muoboghare et al.
British journal of pharmacology, 176(16), 2894-2904 (2019-05-23)
There is a lack of potent, selective antagonists at most subtypes of P2Y receptor. The aims of this study were to characterise the pharmacological properties of the proposed P2Y2 receptor antagonist, AR-C118925XX, and then to use it to determine the
Hui Hong et al.
Cell chemical biology, 26(4), 493-501 (2019-02-05)
Malayamycin A is an unusual bicyclic C-nucleoside, with interesting antiviral, antifungal, and anticancer bioactivity. We report here the discovery and characterization of the biosynthetic pathway to malayamycin by using genome mining of near-identical clusters both from the known producer Streptomyces
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