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Merck
CN

U4125

尿苷 5′-（二磷酸三氢） 钠盐 来源于酿酒酵母

95-100%

别名:

UDP 钠盐, Uridine 5′-(trihydrogen pyrophosphate) 钠盐

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关于此项目

经验公式（希尔记法）:
C9H14N2O12P2 · xNa+
化学文摘社编号:
21931-53-3
分子量:
404.16 (free acid basis)
UNSPSC Code:
12352200
PubChem Substance ID:
24278767
NACRES:
NA.77

主要文件

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SMILES string

[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)N2C=CC(=O)NC2=O

InChI

1S/C9H14N2O12P2.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3

InChI key

GFASEGWJDXDCKZ-UHFFFAOYSA-K

assay

95-100%

solubility

H2O: soluble 100 mg/mL, clear, colorless to very faintly yellow

storage temp.

−20°C

Quality Level

200

Gene Information

human ... LPAR4(2846), LTB4R(1241), P2RY1(5028), P2RY10(27334), P2RY11(5032), P2RY12(64805), P2RY13(53829), P2RY14(9934), P2RY2(5029), P2RY4(5030), P2RY5(10161), P2RY6(5031), P2RY8(286530)

相关类别

Application

UDP已用作嘌呤能激动剂，研究其对耳蜗外沟细胞（OSC）和前庭移行细胞（VTC）吸收阳离子通量的影响 。UDP 还用于兔视网膜中核苷二磷酸酶（NDPase）活性测定 。

Biochem/physiol Actions

P2Y 受体激动剂。

Features and Benefits

该化合物的相关信息整理于受体分类和信号转导手册的 P2受体：P2Y G蛋白家族 页面。想要浏览手册的其他页面， 请单击此处。

Preparation Note

尿苷 5′-（三磷酸二氢钠）钠或 UDP 钠盐溶于水，浓度为 100 mg/mL，成为澄清、无色至微淡黄色溶液。

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H371

Hazard Classifications

STOT SE 2

target_organs

Eyes,Central nervous system

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000432616
0000432616
0000465050
0000465050
0000462968

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J H Lee et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(23), 9168-9174 (2001-11-22)
Cochlear outer sulcus cells (OSC) and vestibular transitional cells (VTC) are part of the parasensory epithelium in the inner ear and are located in homologous positions between the sensory hair cells and the cation secretory epithelial cells in the cochlea
J Schnitzer
The Journal of comparative neurology, 282(2), 249-263 (1989-04-08)
Enzyme-histochemical methods for thiamine pyrophosphatase (TPPase) and nucleoside diphosphatase (NDPase) were applied to wholemounted rabbit retinae to demonstrate the shape and distribution of microglial cells in early postnatal and adult animals. At birth, microglial cells were already present in the
Markie O Muoboghare et al.
British journal of pharmacology, 176(16), 2894-2904 (2019-05-23)
There is a lack of potent, selective antagonists at most subtypes of P2Y receptor. The aims of this study were to characterise the pharmacological properties of the proposed P2Y2 receptor antagonist, AR-C118925XX, and then to use it to determine the
Hui Hong et al.
Cell chemical biology, 26(4), 493-501 (2019-02-05)
Malayamycin A is an unusual bicyclic C-nucleoside, with interesting antiviral, antifungal, and anticancer bioactivity. We report here the discovery and characterization of the biosynthetic pathway to malayamycin by using genome mining of near-identical clusters both from the known producer Streptomyces
Dhébora Albuquerque Dias et al.
Cell biochemistry and function, 35(7), 358-363 (2017-09-06)
This study aimed to characterize the activity of ectonucleoside triphosphate diphosphohydrolase (E-NTPDase; EC 3.6.1.5) in peritoneal cavity cells from BALB/c mice. E-NTPDase was activated in the presence of both calcium (1.5mM) and magnesium (1.5mM) ions. However, the activity was higher
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实验方案

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

LC/MS Analysis of Nucleotides SeQuant® ZIC®-cHILIC – Effect of pH

ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

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