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Merck
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PRKCQ

protein kinase C, theta

别名:
PRKCT, nPKC-theta
物种:
UniProtKB ID:
基因ID:
  • Human(5588) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]
  • Mouse(18761) protein kinase C, theta
  • Rat(85420) protein kinase C, theta
  • cow(505901) protein kinase C, theta
  • Zebrafish(555521) protein kinase C, theta
  • Horse(100070207) protein kinase C, theta
  • domestic guinea pig(100726308) protein kinase C, theta
  • naked mole-rat(101724103) protein kinase C, theta
  • domestic cat(101100730) protein kinase C, theta
  • dog(478013) protein kinase C, theta
  • chicken(776459) protein kinase C, theta
  • sheep(101113426) protein kinase C, theta

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Antibodies

Product Number
说明
物种反应性
应用
Anti-PKCθ Antibody, clone 2J4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, nonhuman primates, rat, sheep
应用
affinity binding assay
immunoprecipitation (IP)

western blot
Anti-Phospho-PRKCQ-T538 antibody produced in rabbit, ,
物种反应性
human
应用
western blot
Anti-phospho-PRKCQ (pSer695) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
Anti-PKC THET antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
Anti-PRKCQ antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

Small Molecule - Inhibitor

Product Number
说明
物种
GSK690693, ≥98% (HPLC),
物种
human

Proteins

Product Number
说明
物种
N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸, ,
物种
mouse
PKC θ Protein, active, 10 µg, Active, recombinant full-length human PKC theta with a C-terminal 6His-tag. For use in Kinase Assays.,
物种
human

esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting mouse Prkcq,
物种
mouse
MISSION® esiRNA, targeting human PRKCQ,
物种
human