跳转至内容
Merck
CN

XIAP

X-linked inhibitor of apoptosis

别名:
API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3
物种:
Human XIAP (331), Mouse Xiap (11798), Rat Xiap (63879), domestic cat XIAP (101090594), chicken XIAP (395280), dog XIAP (442989), Domestic Rabbit XIAP (100328700), cow XIAP (281647), Horse XIAP (100060870), Zebrafish xiap (373108) ...展开
UniProtKB ID:
P98170, D3DTF2, Q9NQ14
基因ID:
  • Human(331) Summary: This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]
  • Mouse(11798) X-linked inhibitor of apoptosis
  • Rat(63879) X-linked inhibitor of apoptosis
  • domestic cat(101090594) X-linked inhibitor of apoptosis
  • chicken(395280) X-linked inhibitor of apoptosis
  • dog(442989) X-linked inhibitor of apoptosis
  • Domestic Rabbit(100328700) X-linked inhibitor of apoptosis
  • cow(281647) X-linked inhibitor of apoptosis
  • Horse(100060870) X-linked inhibitor of apoptosis
  • Zebrafish(373108) X-linked inhibitor of apoptosis
  • domestic guinea pig(100715778) X-linked inhibitor of apoptosis
  • naked mole-rat(101715865) X-linked inhibitor of apoptosis
  • sheep(101116381) X-linked inhibitor of apoptosis

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

产品编号
说明
物种
RAB0860
小鼠Xiap / E3泛素蛋白连接酶XIAP ELISA试剂盒, ,
物种
mouse
RAB0517
Human XIAP ELISA Kit, for serum, plasma, cell culture supernatant and urine,
物种
human
RAB0921
大鼠Xiap / E3泛素蛋白连接酶XIAP ELISA试剂盒, ,
物种
rat

Small Molecule - Antagonist

产品编号
说明
物种
E1406
恩贝酸, ≥98% (HPLC), powder,
物种
human

Antibodies

产品编号
说明
物种反应性
应用
SAB5700239
Anti-XIAP antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
PRS3331
Anti-XIAP antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
ZRB1709
Anti-XIAP Antibody, clone 3H4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
HPA042428
Anti-XIAP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
SAB1403557
Monoclonal Anti-BIRC4 antibody produced in mouse, clone 1F4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
proximity ligation assay
western blot

Proteins

产品编号
说明
物种
SRP0230
XIAP Active human, recombinant, expressed in baculovirus infected insect cells, ≥65% (SDS-PAGE),
物种
human

esiRNA

产品编号
说明
物种
EMU003031
MISSION® esiRNA, targeting mouse Xiap,
物种
mouse
EHU111091
MISSION® esiRNA, targeting human XIAP,
物种
human