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线性分子式:
HN=C(NH2)NH(CH2)3CH(NH2)COOCH3 · 2HCl
化学文摘社编号:
分子量:
261.15
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
247-622-0
Beilstein/REAXYS Number:
4159929
MDL number:
InChI key
XQYZOBNLCUAXLF-XRIGFGBMSA-N
InChI
1S/C7H16N4O2.2ClH/c1-13-6(12)5(8)3-2-4-11-7(9)10;;/h5H,2-4,8H2,1H3,(H4,9,10,11);2*1H/t5-;;/m0../s1
SMILES string
Cl.Cl.COC(=O)[C@@H](N)CCCNC(N)=N
assay
≥98.0% (AT)
form
powder
optical activity
[α]20/D +21±1°, c = 2.5% in methanol
reaction suitability
reaction type: solution phase peptide synthesis
color
white
mp
~190 °C (dec.)
application(s)
peptide synthesis
Quality Level
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Alessandro Rubini
Respiration; international review of thoracic diseases, 82(5), 468-475 (2011-08-09)
Data describing the inhibitory effects of nitric oxide synthase (NOS) on respiratory mechanics are conflicting, and no data are available concerning possible effects on the viscoelasticity of the respiratory system, on the inspiratory work of breathing (WOB) or on respiratory
Matthew F Bush et al.
Journal of the American Chemical Society, 129(6), 1612-1622 (2007-01-26)
The gas-phase structures of protonated and alkali metal cationized arginine (Arg) and arginine methyl ester (ArgOMe) are investigated with infrared spectroscopy and ab initio calculations. Infrared spectra, measured in the hydrogen-stretch region, provide compelling evidence that arginine changes from its
Matthew W Forbes et al.
The journal of physical chemistry. A, 111(46), 11759-11770 (2007-11-02)
The structures of cationized arginine complexes [Arg + M]+, (M = H, Li, Na, K, Rb, Cs, and Ag) and protonated arginine methyl ester [ArgOMe + H]+ have been investigated in the gas phase using calculations and infrared multiple-photon dissociation
Nebivolol decreases endothelial cell stiffness via the estrogen receptor beta: a nano-imaging study.
Uta Hillebrand et al.
Journal of hypertension, 27(3), 517-526 (2009-03-31)
Nebivolol (NEB) is a [beta]1-receptor blocker with nitric oxide-dependent vasodilating properties. NEB-induced nitric oxide release is mediated through the estrogen receptor. Here, we tested the hypothesis that NEB decreases endothelial cell stiffness and that these effects can be abolished by
Anand Kumar et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 292(5), R1900-R1906 (2007-01-20)
Previous studies have demonstrated the presence of myocardial depression in clinical and experimental septic shock. This response is mediated, in part, through circulating TNF-alpha-induced, nitric oxide-dependent, depression of basal myocyte contractility. Other mechanisms of early myocardial dysfunction involving decreased response
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