128201
N-乙基-邻巴豆酰甲基苯胺
97%
别名:
克罗米通
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线性分子式:
CH3CH=CHCON(C2H5)C6H4CH3
化学文摘社编号:
分子量:
203.28
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
207-596-3
MDL number:
产品名称
N-乙基-邻巴豆酰甲基苯胺, 97%
InChI key
DNTGGZPQPQTDQF-XBXARRHUSA-N
InChI
1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3/b8-4+
SMILES string
CCN(C(=O)\C=C\C)c1ccccc1C
description
predominantly trans
assay
97%
form
solid
refractive index
n20/D 1.54 (lit.)
bp
153-155 °C/13 mmHg (lit.)
solubility
ethanol: soluble
methanol: soluble
density
0.987 g/mL at 25 °C (lit.)
Quality Level
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Application
N-Ethyl-o-crotonotoluidide ( Crotamiton) was used to study the photocatalytic decomposition of crotamiton in aqueous solution using TiO2.
N-Ethyl-o-crotonotoluidide (Crotamiton) was used to treat scabies and various pruritic dermatoses.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
The use of N-ethyl-o-crotonotoluidide in the treatment of scabies and various pruritic dermatoses.
M COUPERUS
The Journal of investigative dermatology, 13(1), 35-42 (1949-07-01)
Allergic contact dermatitis due to crotamiton.
H Hara et al.
Contact dermatitis, 49(4), 219-219 (2004-03-05)
Kyoung-Jin Kim et al.
Pediatric dermatology, 19(5), 409-411 (2002-10-18)
Misdiagnosis is frequent in scabies of infants and children because of a low index of suspicion, secondary eczematous changes, and inappropriate therapy. Topical or systemic corticosteroids may modify the clinical presentation of scabies and that situation is referred to as
Demodecidosis manifested on the external genitalia.
S M Hwang et al.
International journal of dermatology, 37(8), 634-636 (1998-09-10)
Ulrich R Hengge et al.
The Lancet. Infectious diseases, 6(12), 769-779 (2006-11-25)
Scabies has been a scourge among human beings for thousands of years. Its worldwide occurrence with epidemics during war, famine, and overcrowding is responsible for an estimated 300 million people currently infested. Scabies refers to the various skin lesions produced
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