149837
2-乙氧基-1-乙氧羰基-1,2-二氢喹啉
≥99%, for peptide synthesis
别名:
2-乙氧基-1,2-二氢-1-喹啉羧酸乙酯, N-乙氧羰基-2-乙氧基-1,2-二氢喹啉, EEDQ
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关于此项目
经验公式（希尔记法）:
C14H17NO3
化学文摘社编号:
分子量:
247.29
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
EC Number:
240-418-2
MDL number:
Beilstein/REAXYS Number:
533048
产品名称
2-乙氧基-1-乙氧羰基-1,2-二氢喹啉, ≥99%
InChI key
GKQLYSROISKDLL-UHFFFAOYSA-N
InChI
1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3
SMILES string
CCOC1C=Cc2ccccc2N1C(=O)OCC
assay
≥99%
form
solid
reaction suitability
reaction type: Coupling Reactions
mp
62-67 °C (lit.)
application(s)
peptide synthesis
functional group
ether
storage temp.
2-8°C
Quality Level
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Application
2-乙氧基-1-乙氧羰基-1,2-二氢喹啉用作偶联剂：
- 用于壳聚糖及其两亲性衍生物的区域选择性季铵化。
- 用于制备酰胺型S-MA（扁桃酸）衍生物修饰的石英晶体微天平(QCM)传感器。
General description
2-乙氧基-1-乙氧羰基-1,2-二氢喹啉(EEDQ)是稳定试剂，可用于高产率制备酰胺和多肽。本品提供现成货品。室温下，可溶于含有机溶剂的水性介质，但不溶于水。 用作肽合成偶联剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Toshiaki Miki et al.
Journal of biochemistry, 141(3), 377-387 (2007-01-20)
Chemical modification of the bovine heart cytochrome bc1 complex with N-(ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinoline (EEDQ) has been reported to inhibit the proton pumping activity without affecting the rate of electron transfer to ferricytochrome c. This study aims to examine the effect of EEDQ
S Kapur et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 23(5), 595-598 (2000-10-12)
Two techniques are commonly used to measure antipsychotic induced dopamine D(2) occupancy in animals: competition with a reversible radioligand (3H-raclopride) or with an irreversible receptor inactivator (EEDQ). While both of these techniques have been used in the past, there is
Development of real-time sensitive chiral analysis technique using quartz crystal analyzer
Kim JM, et al.
Sensors and Actuators B, Chemical, 171, 478-485 (2012)
Didier Cussac et al.
Molecular pharmacology, 62(3), 578-589 (2002-08-16)
As determined by a guanosine 5'-O-(3-[(35)S]thio)triphosphate ([(35)S]GTPgammaS) binding assay, which does not distinguish G protein subtypes, 5-hydroxytryptamine (5-HT) and 2(S)- 1-(6-chloro-5-fluoro-1H-indol-1-yl)-2-propanamine fumarate (Ro600175) behaved as full agonists at human 5-HT(2C) (h5-HT(2C)) receptors (VSV isoform) stably expressed in Chinese hamster ovary
G D Stanwood et al.
The Journal of pharmacology and experimental therapeutics, 295(3), 1232-1240 (2000-11-18)
Regulation of the expression of dopamine D2 and D3 receptors in the rat brain was examined using quantitative autoradiography after chronic (14 day) drug treatments designed to increase or decrease dopamine receptor stimulation. Reserpine treatment depleted endogenous dopamine by more
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