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Merck
CN

15500

N-(叔丁氧羰基)-L-丝氨酸

≥99.0% (T), for peptide synthesis

别名:

N-(叔丁氧羰基)-L-丝氨酸, Boc-L-丝氨酸

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关于此项目

线性分子式:
HOCH2CH(COOH)NHCOOC(CH3)3
化学文摘社编号:
分子量:
205.21
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
221-867-3
MDL number:
Beilstein/REAXYS Number:
2212252
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产品名称

N-(叔丁氧羰基)-L-丝氨酸, ≥99.0% (T)

Quality Level

assay

≥99.0% (T)

optical activity

[α]20/D −3.5±0.5°, c = 2% in acetic acid

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

91 °C (dec.) (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

CC(C)(C)OC(=O)N[C@@H](CO)C(O)=O

InChI

1S/C8H15NO5/c1-8(2,3)14-7(13)9-5(4-10)6(11)12/h5,10H,4H2,1-3H3,(H,9,13)(H,11,12)/t5-/m0/s1

InChI key

FHOAKXBXYSJBGX-YFKPBYRVSA-N

General description

Boc-Ser-OH是一种氨基酸衍生物。

Application

Boc-Ser-OH可用于以下合成:
  • 2-(N-Fmoc)-3-(N-BOC-N-甲氧基)-二氨基丙酸(Fmoc:9-芴基甲氧基羰基;Boc:叔丁氧基羰基)
  • Boc-Ser-Leu-OMe
  • 环肽合成
  • 苄基磺酰基-D-Ser-Ser-4-氨基苄酰胺
肽合成中的结构单元。用于通过 β-内酯合成各种 α-氨基酸的原料。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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O García-Suárez et al.
Immunology, 94(2), 235-241 (1998-09-19)
Increasing evidence suggests that some members of the neurotrophic factor family of neurotrophins could be implicated in the regulation of immune responses. Neurotrophins, as well as their tyrosine kinase signal-transducing receptors (the so-called Trk neurotrophin receptors), have been detected in
Gema Villa-Fombuena et al.
Development (Cambridge, England), 148(18) (2021-08-10)
Drosophila female germline stem cells (GSCs) are found inside the cellular niche at the tip of the ovary. They undergo asymmetric divisions to renew the stem cell lineage and to produce sibling cystoblasts that will in turn enter differentiation. GSCs
Synthesis of cyclic peptides via O-N-acyl migration.
Lecaillon J, et al.
Tetrahedron Letters, 49(31), 4674-4676 (2008)



全球贸易项目编号

货号GTIN
15500-5G04061832641614
15500-25G04061832641607