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Merck
CN

165344

Sigma-Aldrich

1-(3-二甲基氨丙基)-3-乙基碳二亚胺甲碘盐

for peptide synthesis

别名:

EDC 甲基碘化物

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关于此项目

线性分子式:
C2H5N=C=N(CH2)3N(CH3)3I
CAS Number:
分子量:
297.18
EC 号:
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.22
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Product Name

1-(3-二甲基氨丙基)-3-乙基碳二亚胺甲碘盐,

表单

powder

质量水平

反应适用性

reaction type: Coupling Reactions

mp

97-99 °C (lit.)

应用

peptide synthesis

官能团

amine

储存温度

2-8°C

SMILES字符串

[I-].CCN=C=NCCC[N+](C)(C)C

InChI

1S/C9H20N3.HI/c1-5-10-9-11-7-6-8-12(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1

InChI key

AGSKWMRPXWHSPF-UHFFFAOYSA-M

应用

  • 交联剂

反应物用于:
  • 酰胺键形成(酰胺化)交联反应
蛋白质的水溶性羧基改性剂。

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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P E Row et al.
Journal of experimental botany, 52(354), 57-66 (2001-02-22)
In order to identify functionally important amino acid residues in the chloroplast protein import machinery, chloroplasts were preincubated with amino-acid-modifying reagents and then allowed to import or form early import intermediates with precursor proteins. Incubation of chloroplasts with N-ethyl maleimide
I Iu Ponedel'kina et al.
Bioorganicheskaia khimiia, 32(5), 524-529 (2006-10-18)
Heparin was modified at carboxyl groups by reaction with several pharmacologically important amino-containing compounds in aqueous medium in the presence of 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide. In dependence on the nature of the amine and the ratio of reagents, conjugates containing 36-100% amide and
Zainub Khan et al.
Drug delivery, 10(3), 213-220 (2003-08-29)
Low density lipoproteins (LDL) have been cationized using the water-soluble carbodiimide, N-ethyl-N'-(3-trimethylpropylammonium) carbodiimide iodide at a reagent: lipoprotein mole ratio of 10 000:1. This was shown to increase the innate DNA-binding capacity of LDL 10-fold. [125I]-labeled carbodiimide-modified LDL ([125I])-labeled ECDI-LDL)
Hiroyuki Iwamoto et al.
Journal of molecular biology, 317(5), 707-720 (2002-04-17)
The regulatory protein system in the skeletal muscle thin filaments is known to exhibit three discrete states, called "off" or "blocked" (no Ca2+), "on" or "closed" (with Ca2+ alone) and "potentiated" or "open" (with strongly bound myosin head) states. Biochemical
Ana Kosoy et al.
Biological research, 36(3-4), 389-404 (2003-11-25)
Transducin (T), a GTP-binding protein involved in phototransduction of rod photoreceptor cells, is a heterotrimer arranged as two units, the alpha-subunit (T alpha) and the beta gamma-complex (T beta gamma). The role of the carboxyl groups in T was evaluated

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