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Merck
CN

165344

Sigma-Aldrich

1-(3-二甲基氨丙基)-3-乙基碳二亚胺甲碘盐

for peptide synthesis

别名:

EDC 甲基碘化物

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关于此项目

线性分子式:
C2H5N=C=N(CH2)3N(CH3)3I
化学文摘社编号:
分子量:
297.18
EC 号:
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.22
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产品名称

1-(3-二甲基氨丙基)-3-乙基碳二亚胺甲碘盐,

表单

powder

反应适用性

reaction type: Coupling Reactions

mp

97-99 °C (lit.)

应用

peptide synthesis

官能团

amine

储存温度

2-8°C

SMILES字符串

[I-].CCN=C=NCCC[N+](C)(C)C

InChI

1S/C9H20N3.HI/c1-5-10-9-11-7-6-8-12(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1

InChI key

AGSKWMRPXWHSPF-UHFFFAOYSA-M

应用

  • 交联剂

反应物用于:
  • 酰胺键形成(酰胺化)交联反应
蛋白质的水溶性羧基改性剂。

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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I Iu Ponedel'kina et al.
Bioorganicheskaia khimiia, 32(5), 524-529 (2006-10-18)
Heparin was modified at carboxyl groups by reaction with several pharmacologically important amino-containing compounds in aqueous medium in the presence of 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide. In dependence on the nature of the amine and the ratio of reagents, conjugates containing 36-100% amide and
Zainub Khan et al.
Drug delivery, 10(3), 213-220 (2003-08-29)
Low density lipoproteins (LDL) have been cationized using the water-soluble carbodiimide, N-ethyl-N'-(3-trimethylpropylammonium) carbodiimide iodide at a reagent: lipoprotein mole ratio of 10 000:1. This was shown to increase the innate DNA-binding capacity of LDL 10-fold. [125I]-labeled carbodiimide-modified LDL ([125I])-labeled ECDI-LDL)
Mou-Chieh Kao et al.
Biochemistry, 43(12), 3750-3755 (2004-03-24)
The proton-translocating NADH-quinone oxidoreductase (NDH-1) of Paracoccus denitrificans is composed of 14 different subunits (designated Nqo1-14), seven of which are located in the membrane domain and the other seven in the peripheral domain. It has been previously reported that membrane
P E Row et al.
Journal of experimental botany, 52(354), 57-66 (2001-02-22)
In order to identify functionally important amino acid residues in the chloroplast protein import machinery, chloroplasts were preincubated with amino-acid-modifying reagents and then allowed to import or form early import intermediates with precursor proteins. Incubation of chloroplasts with N-ethyl maleimide
Edit Csapó et al.
Carbohydrate polymers, 195, 99-106 (2018-05-29)
This work demonstrates the preparation, structural characterization, and the kinetics of the drug release of hyaluronic acid (HyA)-based colloidal drug delivery systems which contain hydrophobic ketoprofen (KP) as model molecule. Because of the highly hydrophilic character of HyA the cross-linked

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