16599
4-(三氟甲基)-L-苯基甘氨酸
≥98.0%
别名:
(S)-2-氨基-2-[4-(三氟甲基)苯基]乙酸
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关于此项目
经验公式（希尔记法）:
C9H8F3NO2
化学文摘社编号:
分子量:
219.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
InChI
1S/C9H8F3NO2/c10-9(11,12)6-3-1-5(2-4-6)7(13)8(14)15/h1-4,7H,13H2,(H,14,15)/t7-/m0/s1
SMILES string
N[C@H](C(O)=O)c1ccc(cc1)C(F)(F)F
InChI key
FANMQHUKZBBELZ-ZETCQYMHSA-N
assay
≥98.0%
reaction suitability
reaction type: solution phase peptide synthesis
application(s)
peptide synthesis
Quality Level
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Jingliang Zhang et al.
Cell reports, 36(5), 109495-109495 (2021-08-05)
Scn2a encodes the voltage-gated sodium channel NaV1.2, a main mediator of neuronal action potential firing. The current paradigm suggests that NaV1.2 gain-of-function variants enhance neuronal excitability, resulting in epilepsy, whereas NaV1.2 deficiency impairs neuronal excitability, contributing to autism. However, this
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