171824
DL-脯氨酸
99%, for peptide synthesis, ReagentPlus®
别名:
(±)-吡咯烷-2-羧酸
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关于此项目
经验公式（希尔记法）:
C5H9NO2
化学文摘社编号:
分子量:
115.13
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
210-189-3
MDL number:
Beilstein/REAXYS Number:
80812
产品名称
DL-脯氨酸, ReagentPlus®, 99%
Quality Level
product line
ReagentPlus®
assay
99%
form
powder
reaction suitability
reaction type: solution phase peptide synthesis
mp
208 °C (dec.) (lit.)
application(s)
peptide synthesis
SMILES string
OC(=O)C1CCCN1
InChI
1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)
InChI key
ONIBWKKTOPOVIA-UHFFFAOYSA-N
General description
DL-脯氨酸，又名2-吡咯烷羧酸，是一种氨基酸，具有限制性phi( ϕ)角，常用作多肽固相合成的转角诱导分子。
Application
DL-脯氨酸可用于制备cis-氨基脯氨酸-烯烃(cis-Apa)连接分子，进一步用作液相法多肽合成环状伪肽的中间体。
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
cis-Apa: A practical linker for the microwave-assisted preparation of cyclic pseudopeptides via RCM cyclative cleavage
A Baron
The Journal of Organic Chemistry, 76, 766-772 (2011)
Recent Progress in Solid-Phase Total Synthesis of Naturally Occurring Small Peptides
H Yan
Advanced Synthesis & Catalysis, 364, 1934-1961 (2022)
Antoinette Bugyei-Twum et al.
Cardiovascular diabetology, 13, 89-89 (2014-06-03)
Despite advances in the treatment of heart failure, mortality remains high, particularly in individuals with diabetes. Activated transforming growth factor beta (TGF-β) contributes to the pathogenesis of the fibrotic interstitium observed in diabetic cardiomyopathy. We hypothesized that high glucose enhances
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 171824-25G | 04061833389218 |
| 171824-1G | 04061838530424 |
| 171824-5G | 04061838751256 |