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Merck
CN

192066

聚甲基丙烯酸-2-羟乙酯

average Mv 300,000, crystalline

别名:

聚(2-HEMA), 聚-HEMA

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关于此项目

线性分子式:
(C6H10O3)n
化学文摘社编号:
25249-16-5
NACRES:
NA.23
PubChem Substance ID:
24851526
UNSPSC Code:
12162002
MDL number:
MFCD00084374

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产品名称

聚甲基丙烯酸-2-羟乙酯, average Mv 300,000, crystalline

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

SMILES string

CC(=C)C(=O)OCCO

InChI key

WOBHKFSMXKNTIM-UHFFFAOYSA-N

form

crystalline

mol wt

average Mv 300,000

density

1.15 g/mL at 25 °C (lit.)

Quality Level

200

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相关类别

Application

pHEMA骨架被用于组织工程中。 它可作为金属离子的吸附剂被用于生物医学应用的水凝胶中。pHEMA已被用于如软性隐形眼镜、药物输送系统和肾脏透析膜等应用中。pHEMA的纳米粒子可作为抗癌和抗肿瘤药物的一种受控输送载体。

General description

固相的聚(2-羟乙酯甲基丙烯酸)(pHEMA)是脆性的，而pHEMA水凝胶是一种软材料。pHEMA水凝胶的玻璃化转变温度可通过增加基质中水的含量而降低。 pHEMA的大分子属性是通过聚合物链以及水合水分子之间氢键的非共价相互作用而得以表征的。 每一重复单元上羟基和羧基极性基团的存在使得该聚合物可与水相容。骨架上的疏水a-甲基可将水解稳定性传递给聚合物并提高聚合物基质的机械强度。

Physical form

遇水膨胀聚合物。水凝胶。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
11118TH
10427LH
01126HH
01623BH
06012AH

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Fiber templating of poly (2-hydroxyethyl methacrylate) for neural tissue engineering
Flynn L,et al
Biomaterials, 24(23), 4265-4272 null
W E Roorda et al.
Pharmaceutical research, 5(11), 722-725 (1988-11-01)
The freezing and melting behavior of water in poly hydroxy ethyl methacrylate (pHEMA) hydrogels of different cross-linker and water contents was investigated in relation to the glass transition temperature (Tg) of the gels. After prolonged cooling at -15 degrees C
M Rafiqul Islam et al.
Journal of nanoscience and nanotechnology, 13(1), 603-606 (2013-05-08)
Biocompatible magnetic nanocomposites of Fe-AuNPs and poly(2-hydroxylethyl methacrylate) (PHEMA) were employed as a strategic protein immobilization platform. The hybrid magnetic nanocomposites were prepared by applying a 'grafting to' ATRP protocol. Fe-AuNPs having Fe core and Au shell were initially prepared
Kazım Köse et al.
Artificial cells, nanomedicine, and biotechnology, 41(1), 13-20 (2012-11-01)
The purpose of this article is to synthesize poly(hydroxyethyl methacrylate-N-methacryloyl-(L)-tryptophan) [mPHEMATrp] magnetic nanoparticles for lysozyme purification from chicken egg white. mPHEMATrp nanoparticles (38 nm in diameter) were synthesized by surfactant-free emulsion polymerization. Specific surface area of the mPHEMATrp nanoparticles was
Narrowly dispersed hydrophilic molecularly imprinted polymer nanoparticles for efficient molecular recognition in real aqueous samples including river water, milk, and bovine serum.
Yue Ma et al.
Angewandte Chemie (International ed. in English), 52(5), 1511-1514 (2012-12-21)
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