产品名称
1,1′-羰基二咪唑, ≥97.0% (T)
Quality Level
assay
≥97.0% (T)
form
solid
reaction suitability
reaction type: Carbonylations
greener alternative product characteristics
Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
mp
115-122 °C, 117-122 °C (lit.)
application(s)
peptide synthesis
greener alternative category
storage temp.
2-8°C
SMILES string
O=C(n1ccnc1)n2ccnc2
InChI
1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H
InChI key
PFKFTWBEEFSNDU-UHFFFAOYSA-N
General description
CDI作为一种功能强大的偶联试剂用于多肽合成和有机化学。
We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. 1,1′-carbonyldiimidazole (CDI) is an alternative to highly toxic insidious poison phosgene and thus aligns with the principle "Designing Safer Chemicals". Click here for more information.
Application
使用CDI(1,1′-羰基咪唑):
- 用于活化丙二酸衍生物,以通过轻微脱羧制备羰基咪唑
- 用于活化纤维素膜,以开发免疫传感器。
- 用于合成替代1,3-恶唑[4,5-d]哒嗪酮。
- 作为各种异羟肟酸通过洛森重排转化为异氰酸酯的试剂。
- 用于合成1,3,4-恶二唑衍生物及水中的多肽硫酯。
- 作为酰化剂合成氨基甲酸盐。
Other Notes
可作为咪唑用于酸的活化的反应性试剂:酯、酰胺、酮等的合成。用于固定化酶和亲和配体的试剂;近来作为羰基转移试剂用于各种杂环的合成
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
S.K. Kang et al.
Synthetic Communications, 23, 2219-2219 (1993)
1,1'-Carbonyldiimidazole-mediated immobilization of enzymes and affinity ligands.
M T Hearn
Methods in enzymology, 135, 102-117 (1987-01-01)
Mechanochemical 1, 1′-Carbonyldiimidazole-Mediated Synthesis of Carbamates
Lanzillotto M, et al.
ACS sustainable chemistry & engineering, 11(3), 2882-2889 (2015)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 226610-10G | 04061837580741 |
| 226610-1G | 04061838780287 |
| 21860-100G | 04061838775528 |
| 21860-5G | 04061838775542 |
| 21860-25G | 04061838775535 |
| 21860-500G | 04065265030298 |

