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Merck
CN

219096

Sigma-Aldrich

D -天冬氨酸

99%, for peptide synthesis, ReagentPlus®

别名:

(R)-(-)-氨基琥珀酸, (R)-2-氨基琥珀酸

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关于此项目

线性分子式:
HO2CCH2CH(NH2)CO2H
化学文摘社编号:
分子量:
133.10
Beilstein:
1723529
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.22
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产品名称

D -天冬氨酸, ReagentPlus®, 99%

质量水平

产品线

ReagentPlus®

方案

99%

表单

powder

旋光性

[α]20/D −24°, c = 2.3 in 6 M HCl

光学纯度

ee: 98% (GLC)

反应适用性

reaction type: solution phase peptide synthesis

mp

>300 °C (lit.)

应用

peptide synthesis

SMILES字符串

N[C@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1

InChI key

CKLJMWTZIZZHCS-UWTATZPHSA-N

基因信息

rat ... Slc1a3(29483)

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应用


  • 代谢组学分析鉴定差异代谢物作为急性心肌梗死的生物标志物:这项研究利用代谢组学来鉴定急性心肌梗死的生物标志物,展示了D-天冬氨酸在氨基酸代谢中的作用及其潜在的诊断应用。(Zhou等人,2024年)。

法律信息

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yuanqi Tao et al.
Analytical chemistry, 84(15), 6814-6820 (2012-07-21)
The presence of a single D-amino acid in a peptide is very difficult to detect. Mass spectrometry-based approaches rely on differences in fragmentation between all L-amino acid-containing peptides and single D-amino acid-containing peptides (which are epimers) for identification. The success
Takehiko Yokoyama et al.
Bioscience, biotechnology, and biochemistry, 75(8), 1481-1484 (2011-08-09)
Immunohistochemical localization (cellular localization) of endogenous D-aspartate in the marine brown alga Sargassum fusiforme was investigated by the use of a specific polyclonal antibody raised against D-aspartate. D-Aspartate immunoreactivity was evident in the medullary layer in the blade of the
Edi Erwan et al.
Amino acids, 43(5), 1969-1976 (2012-04-03)
Intracerebroventricular (i.c.v.) administration of L-aspartate (L-Asp) attenuates stress responses in neonatal chicks, but the mechanism has not been clarified. In the present study, three behavioral experiments were carried out under socially isolated stressful conditions exacerbated by the use of corticotrophin-releasing
Yuichi Kaji et al.
The British journal of ophthalmology, 96(8), 1127-1131 (2012-06-15)
Gelatinous drop-like corneal dystrophy (GDLD), also known as familial subepithelial corneal amyloidosis, is an autosomal recessive disorder that causes progressive corneal opacity due to accumulation of amyloid fibrils in the corneal stroma. Genetic analyses have revealed that a mutation in
Nobutoshi Ota et al.
Amino acids, 43(5), 1873-1886 (2012-08-09)
D-Aspartate (D-Asp) is an endogenous amino acid in the central nervous and reproductive systems of vertebrates and invertebrates. High concentrations of D-Asp are found in distinct anatomical locations, suggesting that it has specific physiological roles in animals. Many of the

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