219096
D -天冬氨酸
99%, for peptide synthesis, ReagentPlus®
别名:
(R)-(-)-氨基琥珀酸, (R)-2-氨基琥珀酸
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关于此项目
线性分子式:
HO2CCH2CH(NH2)CO2H
化学文摘社编号:
分子量:
133.10
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
217-234-6
MDL number:
Beilstein/REAXYS Number:
1723529
产品名称
D -天冬氨酸, ReagentPlus®, 99%
InChI key
CKLJMWTZIZZHCS-UWTATZPHSA-N
InChI
1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1
SMILES string
N[C@H](CC(O)=O)C(O)=O
product line
ReagentPlus®
assay
99%
form
powder
optical activity
[α]20/D −24°, c = 2.3 in 6 M HCl
optical purity
ee: 98% (GLC)
reaction suitability
reaction type: solution phase peptide synthesis
mp
>300 °C (lit.)
application(s)
peptide synthesis
Quality Level
Gene Information
rat ... Slc1a3(29483)
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Application
- 代谢组学分析鉴定差异代谢物作为急性心肌梗死的生物标志物：这项研究利用代谢组学来鉴定急性心肌梗死的生物标志物，展示了D-天冬氨酸在氨基酸代谢中的作用及其潜在的诊断应用。（Zhou等人，2024年）。
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Yuichi Kaji et al.
The British journal of ophthalmology, 96(8), 1127-1131 (2012-06-15)
Gelatinous drop-like corneal dystrophy (GDLD), also known as familial subepithelial corneal amyloidosis, is an autosomal recessive disorder that causes progressive corneal opacity due to accumulation of amyloid fibrils in the corneal stroma. Genetic analyses have revealed that a mutation in
Nobutoshi Ota et al.
Amino acids, 43(5), 1873-1886 (2012-08-09)
D-Aspartate (D-Asp) is an endogenous amino acid in the central nervous and reproductive systems of vertebrates and invertebrates. High concentrations of D-Asp are found in distinct anatomical locations, suggesting that it has specific physiological roles in animals. Many of the
Edi Erwan et al.
Amino acids, 43(5), 1969-1976 (2012-04-03)
Intracerebroventricular (i.c.v.) administration of L-aspartate (L-Asp) attenuates stress responses in neonatal chicks, but the mechanism has not been clarified. In the present study, three behavioral experiments were carried out under socially isolated stressful conditions exacerbated by the use of corticotrophin-releasing
Takehiko Yokoyama et al.
Bioscience, biotechnology, and biochemistry, 75(8), 1481-1484 (2011-08-09)
Immunohistochemical localization (cellular localization) of endogenous D-aspartate in the marine brown alga Sargassum fusiforme was investigated by the use of a specific polyclonal antibody raised against D-aspartate. D-Aspartate immunoreactivity was evident in the medullary layer in the blade of the
Yuhei Mori et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3303-3309 (2011-06-04)
UV-B irradiation is one of the risk factors in age-related diseases. We have reported that biologically uncommon D-β-Asp residues accumulate in proteins from sun-exposed elderly human skin. A previous study also reported that carboxymethyl lysine (CML; one of the advanced
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